Denver Broncos at Seattle Seahawks (-4.5)
The Seahawks would be the pick even if they hadn’t torn apart the Broncos in Super Bowl XLVIII. Seattle is coming off their first loss in months and will be playing in front of their insanely intense home crowd.
Denver won’t go undefeated through the season, nor should they win 13 games for the third consecutive year. The losses have to come from somewhere, and the team with the defense that could stop Manning and the blueprint — not to mention, history — to do so will be the first to knock off the Broncos.
Seahawks win by a touchdown and cover.
