Fantasy Football Defensive Matchup Exploitation

The most and least favorable fantasy football quarterback matchups for Week 13.

The most and least favorable fantasy football running back matchups for Week 13.

The most and least favorable fantasy football wide receiver matchups for Week 13.

The most and least favorable fantasy football tight end matchups for Week 13.

As we saw in Sunday’s matchup between the Seahawks and 49ers, even the best quarterbacks aren’t matchup proof.

Running backs are usually the lifeblood of your fantasy roster so if you run into a tough matchup, it could ruin your entire week.

Sometimes even the best wide receivers run into impossible matchups. We saw what happened when Anquan Boldin faced off one-on-one with Richard Sherman. A seven-yard day.

Just because a team has a good defense doesn’t mean they can cover tight ends.